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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-ELANE Monoclonal Antibody (9F435)

Synonyms: SCN1, PMN-E, NE, HNE, HLE, GE, ELA2
货号 TMAT-0754 一键复制产品信息
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Anti-ELANE Monoclonal Antibody (9F435) 是一种 Mouse 抗体，靶向 ELANE。Anti-ELANE Monoclonal Antibody (9F435) 可用于 WB,IHC,FCM。

Anti-ELANE Monoclonal Antibody (9F435)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0754

别名 SCN1, PMN-E, NE, HNE, HLE, GE, ELA2

Anti-ELANE Monoclonal Antibody (9F435) 是一种 Mouse 抗体，靶向 ELANE。Anti-ELANE Monoclonal Antibody (9F435) 可用于 WB,IHC,FCM。

Anti-ELANE Monoclonal Antibody (9F435)
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产品介绍

生物活性
产品描述
Anti-ELANE Monoclonal Antibody (9F435) is a Mouse antibody targeting ELANE. Anti-ELANE Monoclonal Antibody (9F435) can be used in WB,IHC,FCM.
别名
SCN1, PMN-E, NE, HNE, HLE, GE, ELA2
Ig Type
IgG1
克隆号
9F435
反应种属
Human,Monkey
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human ELANE (AA: 140-267) expressed in E. Coli.
抗原种属
Human
基因名称
ELANE
基因ID
1991
蛋白名称
Neutrophil elastase
Uniprot ID
P08246
化学信息
分子量Theoretical: 28.5 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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