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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-E7 Monoclonal Antibody (5H750)

Synonyms: HpV16gp2, E7
货号 TMAT-0671 一键复制产品信息
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Anti-E7 Monoclonal Antibody (5H750) 是一种 Mouse 抗体，靶向 E7。Anti-E7 Monoclonal Antibody (5H750) 可用于 IHC。

Anti-E7 Monoclonal Antibody (5H750)

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货号 TMAT-0671

别名 HpV16gp2, E7

Anti-E7 Monoclonal Antibody (5H750) 是一种 Mouse 抗体，靶向 E7。Anti-E7 Monoclonal Antibody (5H750) 可用于 IHC。

Anti-E7 Monoclonal Antibody (5H750)
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产品介绍

生物活性
产品描述
Anti-E7 Monoclonal Antibody (5H750) is a Mouse antibody targeting E7. Anti-E7 Monoclonal Antibody (5H750) can be used in IHC.
别名
HpV16gp2, E7
Ig Type
IgG1
克隆号
5H750
反应种属
Virus
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide.
浓度1 mg/mL
研究背景Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of E7 expressed in E. Coli.
抗原种属
Virus
基因名称
E7
基因ID
1489079
蛋白名称
Protein E7
Uniprot ID
P03129
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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