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Anti-E2F1 Monoclonal Antibody (3Z145)

Synonyms: RBP3, RBBP3, RBAP1, E2F-1
货号 TMAT-1188 一键复制产品信息
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Anti-E2F1 Monoclonal Antibody (3Z145) 是一种 Mouse 抗体,靶向 E2F1。Anti-E2F1 Monoclonal Antibody (3Z145) 可用于 WB,IHC,FCM。

Anti-E2F1 Monoclonal Antibody (3Z145)

一键复制产品信息
Rating icon 还可以
货号 TMAT-1188

别名 RBP3, RBBP3, RBAP1, E2F-1

Anti-E2F1 Monoclonal Antibody (3Z145) 是一种 Mouse 抗体,靶向 E2F1。Anti-E2F1 Monoclonal Antibody (3Z145) 可用于 WB,IHC,FCM。

Anti-E2F1 Monoclonal Antibody (3Z145)
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产品介绍


生物活性
产品描述
Anti-E2F1 Monoclonal Antibody (3Z145) is a Mouse antibody targeting E2F1. Anti-E2F1 Monoclonal Antibody (3Z145) can be used in WB,IHC,FCM.
别名
RBP3, RBBP3, RBAP1, E2F-1
Ig Type
IgG1
克隆号
3Z145
反应种属
Human,Mouse
应用WBIHCFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human E2F1 (AA: 69-223) expressed in E. Coli.
抗原种属
Human
基因名称
E2F1
基因ID
蛋白名称
Transcription factor E2F1
Uniprot ID
化学信息
分子量Theoretical: 46.9 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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