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Anti-E2F1 Monoclonal Antibody (3Z145) 是一种 Mouse 抗体,靶向 E2F1。Anti-E2F1 Monoclonal Antibody (3Z145) 可用于 WB,IHC,FCM。
别名 RBP3, RBBP3, RBAP1, E2F-1
Anti-E2F1 Monoclonal Antibody (3Z145) 是一种 Mouse 抗体,靶向 E2F1。Anti-E2F1 Monoclonal Antibody (3Z145) 可用于 WB,IHC,FCM。

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| 产品描述 | Anti-E2F1 Monoclonal Antibody (3Z145) is a Mouse antibody targeting E2F1. Anti-E2F1 Monoclonal Antibody (3Z145) can be used in WB,IHC,FCM. |
| 别名 | RBP3, RBBP3, RBAP1, E2F-1 |
| Ig Type | IgG1 |
| 克隆号 | 3Z145 |
| 反应种属 | Human,Mouse |
| 应用 | WBIHCFCM |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human E2F1 (AA: 69-223) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | E2F1 |
| 基因ID | |
| 蛋白名称 | Transcription factor E2F1 |
| Uniprot ID |
| 分子量 | Theoretical: 46.9 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |