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Anti-Dysferlin interacting protein 1 Polyclonal Antibody

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货号 TMAB-05370

Anti-Dysferlin interacting protein 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Dysferlin interacting protein 1。Anti-Dysferlin interacting protein 1 Polyclonal Antibody 可用于 WB。

Anti-Dysferlin interacting protein 1 Polyclonal Antibody

Anti-Dysferlin interacting protein 1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05370

Anti-Dysferlin interacting protein 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Dysferlin interacting protein 1。Anti-Dysferlin interacting protein 1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Dysferlin interacting protein 1 Polyclonal Antibody is a Rabbit antibody targeting Dysferlin interacting protein 1. Anti-Dysferlin interacting protein 1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Dysferlin is a muscle-specific protein that is essential for normal muscle function and development (1). Mutations in the human dysferlin gene, DYSF, which maps to chromosome 2p13.3-p13.1, are associated with limb girdle muscular dystrophy-2B (LGMD-2B) and a related, adult-onset, distal dystrophy known as Miyoshi myopathy (MM) (1,2). Dysferlin localizes to the muscle fiber membrane, but is absent in MM and LGMD-2B muscle (1,3). Dysferlin is detected in 5-6 week embryos, when limbs begin to form regional differentiation (3). Although it is not essential for initial myogenesis, dysferlin appears to be critical for sustained normal function in mature muscle (1). It has been suggested that the absence of dysferlin during development gives rise to the disease phenotype in adulthood (3). Identical mutations in the dysferlin gene can produce more than one myopathy phenotype, indicating that additional genes and/or other factors are also involved in the clinical phenotype (4,5). The DYSF gene has no homology to any other known mammalian gene, but the protein product is related to the spermatogenesis factor fer-1 of Caenorhabditis elegans. The name ‘dysferlin’ combines the role of the gene in producing muscular dystrophy with its homology to C. elegans (6).
抗原信息
免疫原
KLH conjugated synthetic peptide: human Dysferlin interacting protein 1
抗原种属
Human
基因名称
PPP1R27
基因ID
116729
蛋白名称
Protein phosphatase 1 regulatory subunit 27
Uniprot ID
Q86WC6
功能
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
化学信息
分子量Theoretical: 17 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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