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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody

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货号 TMAB-05366

Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Dynein light chain 2, cytoplasmic。Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody

Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05366

Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Dynein light chain 2, cytoplasmic。Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody is a Rabbit antibody targeting Dynein light chain 2, cytoplasmic. Anti-Dynein light chain 2, cytoplasmic Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. The highly conserved DYNLL proteins were originally identified as light chains for microtubule-based motor protein Dynein. In mammals there are two closely related isoforms expressed, DYNLL1 and DYNLL2 which share 93% sequence identity at the protein level. DYNLL1 (Dynein light chain 1) also designated, DLC8 or PIN (Protein inhibitor of neuronal nitric oxide synthase) has been identified as a protein that interacts with NOS1 resulting in NOS1 inhibition. Dimerization is required for NOS1 activity and DYNLL1 has been shown to destabilize the NOS1 dimer. Nitric oxide may be involved in several processes such as apoptosis, synaptogenesis and neuronal development; thus DYNLL1 is implicated in these processes as well. DYNLL1 is a ubiquitously expressed protein that exhibits high expression in testis and moderate expression in brain. DYNLL2 (Dynein light chain 2) is subject to a unique alternative splicing event which is implicated in Myosin Va binding specificity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Dynein light chain 2
抗原种属
Human
基因名称
DYNLL2
基因ID
140735
蛋白名称
Dynein light chain 2, cytoplasmic
Uniprot ID
Q96FJ2
功能
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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