Name: Anti-DSG3 Antibody
Brand: TargetMol
SKU: T9901A-1324
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-DSG3 Antibody is a highly specialized monoclonal antibody target the human desmoglein 3 protein, a critical cadherin-type cell adhesion molecule, inhibition of intercellular junctions between keratinocytes across various preclinical experimental models to modulate epithelial integrity and study the pathophysiology of pemphigus vulgaris.
体外活性	在角质形成细胞实验中，Anti-DSG3 Antibody 破坏了细胞间粘附并诱导了 desmoglein 3 内吞 [1]。
体内活性	在新生小鼠模型中，通过全身给药方式给予 Anti-DSG3 Antibody，诱导了模拟天疱疮表型的基底上水疱 [1]。
别名	抗DSG3 抗体
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P32926
靶点	DSG3

储存&溶解度

存储

Anti-DSG3 Antibody