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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DOK1 Polyclonal Antibody

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货号 TMAB-05276

Anti-DOK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DOK1。Anti-DOK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DOK1 Polyclonal Antibody

Anti-DOK1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05276

Anti-DOK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DOK1。Anti-DOK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-DOK1 Polyclonal Antibody is a Rabbit antibody targeting DOK1. Anti-DOK1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cytoplasm. Isoform 3: Cytoplasm, perinuclear region.
组织特异性Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DOK1
抗原种属
Human
基因名称
DOK1
基因ID
1796
蛋白名称
Docking protein 1
Uniprot ID
Q99704
功能
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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