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Anti-DNA polymerase mu Polyclonal Antibody

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货号 TMAB-05221

Anti-DNA polymerase mu Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DNA polymerase mu。Anti-DNA polymerase mu Polyclonal Antibody 可用于 WB。

Anti-DNA polymerase mu Polyclonal Antibody

Anti-DNA polymerase mu Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05221

Anti-DNA polymerase mu Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DNA polymerase mu。Anti-DNA polymerase mu Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-DNA polymerase mu Polyclonal Antibody is a Rabbit antibody targeting DNA polymerase mu. Anti-DNA polymerase mu Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in a number of tissues. Abundant in thymus.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DNA polymerase mu
抗原种属
Human
基因名称
POLM
基因ID
27434
蛋白名称
DNA-directed DNA/RNA polymerase mu
Uniprot ID
Q9NP87.1
功能
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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