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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DENND1A Polyclonal Antibody

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货号 TMAB-05080

Anti-DENND1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DENND1A。Anti-DENND1A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DENND1A Polyclonal Antibody

Anti-DENND1A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05080

Anti-DENND1A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DENND1A。Anti-DENND1A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-DENND1A Polyclonal Antibody is a Rabbit antibody targeting DENND1A. Anti-DENND1A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction > synapse > presynaptic cell membrane. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Also associated with uncoated vesicles.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human DENND1A
抗原种属
Human
基因名称
DENND1A
基因ID
57706
蛋白名称
DENN domain-containing protein 1A
Uniprot ID
Q8TEH3
功能
Guanine nucleotide exchange factor (GEF) for RAB35. May be involved in the clathrin-mediated endocytosis of synaptic vesicles.
化学信息
分子量Theoretical: 110 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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