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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Cyp2J3 Polyclonal Antibody

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货号 TMAB-04890

Anti-Cyp2J3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Cyp2J3。Anti-Cyp2J3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Cyp2J3 Polyclonal Antibody

Anti-Cyp2J3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04890

Anti-Cyp2J3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Cyp2J3。Anti-Cyp2J3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Cyp2J3 Polyclonal Antibody is a Rabbit antibody targeting Cyp2J3. Anti-Cyp2J3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
组织特异性Abundantly expressed in heart and liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyse regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.
抗原信息
免疫原
KLH conjugated synthetic peptide: rat Cytochrome P450 2J3
抗原种属
Rat
基因名称
Cyp2j3
基因ID
313375
蛋白名称
Cytochrome P450 2J3
Uniprot ID
P51590
功能
This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation mainly to 14,15-, 11,12-, and 8,9-epoxyeicosatrienoic acids (EET). It also acts as an omega-1-hydroxylase by metabolizing arachidonic acid to 19-hydroxyeicosatetraenoic acid (19-OH-AA).
化学信息
分子量Theoretical: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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