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Anti-CREB-1 Polyclonal Antibody 2

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货号 TMAB-04648

Anti-CREB-1 Polyclonal Antibody 2 是一种 Mouse 抗体，靶向 CREB-1。Anti-CREB-1 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CREB-1 Polyclonal Antibody 2

Anti-CREB-1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04648

Anti-CREB-1 Polyclonal Antibody 2 是一种 Mouse 抗体，靶向 CREB-1。Anti-CREB-1 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-CREB-1 Polyclonal Antibody 2 is a Mouse antibody targeting CREB-1. Anti-CREB-1 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Mouse
亚细胞定位Nucleus.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), which may reprecent a CREB co-activator.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CREB-1
抗原种属
Human
基因名称
CREB1
基因ID
1385
蛋白名称
Cyclic AMP-responsive element-binding protein 1
Uniprot ID
P16220
功能
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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