购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-COMP Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04539

Anti-COMP Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 COMP。Anti-COMP Polyclonal Antibody 2 可用于 WB。

Anti-COMP Polyclonal Antibody 2

Anti-COMP Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04539

Anti-COMP Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 COMP。Anti-COMP Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-COMP Polyclonal Antibody 2 is a Rabbit antibody targeting COMP. Anti-COMP Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Rat,Mouse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. Increased amounts are produced during late stages of osteoarthritis in the area adjacent to the main defect.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
抗原信息
免疫原
Recombinant Protein: human COMP protein
抗原种属
Human
基因名称
COMP
基因ID
1311
蛋白名称
Cartilage oligomeric matrix protein
Uniprot ID
P49747
功能
May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.
化学信息
分子量Theoretical: 83 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-COMP Polyclonal Antibody 2 | purchase Anti-COMP Polyclonal Antibody 2 | Anti-COMP Polyclonal Antibody 2 cost | order Anti-COMP Polyclonal Antibody 2 | Anti-COMP Polyclonal Antibody 2 molecular weight