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Anti-CHRNB3 Monoclonal Antibody (6Q249) 是一种 Mouse 抗体,靶向 CHRNB3。Anti-CHRNB3 Monoclonal Antibody (6Q249) 可用于 FCM。
Anti-CHRNB3 Monoclonal Antibody (6Q249) 是一种 Mouse 抗体,靶向 CHRNB3。Anti-CHRNB3 Monoclonal Antibody (6Q249) 可用于 FCM。

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| 产品描述 | Anti-CHRNB3 Monoclonal Antibody (6Q249) is a Mouse antibody targeting CHRNB3. Anti-CHRNB3 Monoclonal Antibody (6Q249) can be used in FCM. |
| Ig Type | IgG1 |
| 克隆号 | 6Q249 |
| 反应种属 | Human |
| 应用 | FCM |
| 推荐剂量 | FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]). Elliott et al. (1996) [PubMed 8906617] stated that the proposed structure for each subunit is a conserved N-terminal extracellular domain followed by 3 conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human CHRNB3 (AA: extra 25-232) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CHRNB3 |
| 基因ID | |
| 蛋白名称 | Neuronal acetylcholine receptor subunit beta-3 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |