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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-CHRNA7 Monoclonal Antibody (3E741)

Synonyms: NACHRA7, CHRNA7-2
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Anti-CHRNA7 Monoclonal Antibody (3E741) 是一种 Mouse 抗体，靶向 CHRNA7。Anti-CHRNA7 Monoclonal Antibody (3E741) 可用于 WB,FCM。

Anti-CHRNA7 Monoclonal Antibody (3E741)

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Rating icon 还可以
货号 TMAT-1001

别名 NACHRA7, CHRNA7-2

Anti-CHRNA7 Monoclonal Antibody (3E741) 是一种 Mouse 抗体，靶向 CHRNA7。Anti-CHRNA7 Monoclonal Antibody (3E741) 可用于 WB,FCM。

Anti-CHRNA7 Monoclonal Antibody (3E741)
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产品介绍

生物活性
产品描述
Anti-CHRNA7 Monoclonal Antibody (3E741) is a Mouse antibody targeting CHRNA7. Anti-CHRNA7 Monoclonal Antibody (3E741) can be used in WB,FCM.
别名
NACHRA7, CHRNA7-2
Ig Type
IgG1
克隆号
3E741
反应种属
Human,Rat
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CHRNA7 (AA: extra 52-259) expressed in E. Coli.
抗原种属
Human
基因名称
CHRNA7
基因ID
1139
蛋白名称
Neuronal acetylcholine receptor subunit alpha-7
Uniprot ID
P36544
化学信息
分子量Theoretical: 56.4 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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