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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Chimaerin 2 Polyclonal Antibody

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货号 TMAB-04302

Anti-Chimaerin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Chimaerin 2。Anti-Chimaerin 2 Polyclonal Antibody 可用于 WB。

Anti-Chimaerin 2 Polyclonal Antibody

Anti-Chimaerin 2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04302

Anti-Chimaerin 2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Chimaerin 2。Anti-Chimaerin 2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Chimaerin 2 Polyclonal Antibody is a Rabbit antibody targeting Chimaerin 2. Anti-Chimaerin 2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Peripheral membrane protein
组织特异性Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Chimaerin 2
抗原种属
Human
基因名称
CHN2
基因ID
1124
蛋白名称
beta-chimaerin
Uniprot ID
P52757
功能
The Chimaerin gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, an SH2 domain and a Rho-GAP domain. This protein has GTPase-activating protein activity which is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Increased expression of this gene is associated with lymphomas and decreased expression of this gene is associated with high-grade gliomas and breast tumors. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
化学信息
分子量Theoretical: 54 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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