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Anti-CDK4 Monoclonal Antibody (1R128)

Synonyms: PSK-J3, CMM3
货号 TMAT-0478 一键复制产品信息
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Anti-CDK4 Monoclonal Antibody (1R128) 是一种 Mouse 抗体,靶向 CDK4。Anti-CDK4 Monoclonal Antibody (1R128) 可用于 IHC,IF,FCM。

Anti-CDK4 Monoclonal Antibody (1R128)

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货号 TMAT-0478

别名 PSK-J3, CMM3

Anti-CDK4 Monoclonal Antibody (1R128) 是一种 Mouse 抗体,靶向 CDK4。Anti-CDK4 Monoclonal Antibody (1R128) 可用于 IHC,IF,FCM。

Anti-CDK4 Monoclonal Antibody (1R128)
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产品介绍


生物活性
产品描述
Anti-CDK4 Monoclonal Antibody (1R128) is a Mouse antibody targeting CDK4. Anti-CDK4 Monoclonal Antibody (1R128) can be used in IHC,IF,FCM.
别名
PSK-J3, CMM3
Ig Type
IgG1
克隆号
1R128
反应种属
Human
应用IHCIFFCM
推荐剂量
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CDK4 (AA: 77-303) expressed in E. Coli.
抗原种属
Human
基因名称
CDK4
基因ID
蛋白名称
Cyclin-dependent kinase 4
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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