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Anti-CD162 Polyclonal Antibody 2

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货号 TMAB-03864

Anti-CD162 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 CD162。Anti-CD162 Polyclonal Antibody 2 可用于 WB。

Anti-CD162 Polyclonal Antibody 2

Anti-CD162 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-03864

Anti-CD162 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 CD162。Anti-CD162 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-CD162 Polyclonal Antibody 2 is a Rabbit antibody targeting CD162. Anti-CD162 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Expressed on neutrophils, monocytes and most lymphocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse PSGL-1/CD162
抗原种属
Mouse
基因名称
SELPLG
基因ID
蛋白名称
P-selectin glycoprotein ligand 1
Uniprot ID
功能
A SLe(x)-type glycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. PSGL1 is critical for the initial leukocyte capture.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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