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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD158D Monoclonal Antibody (6W258)

Synonyms: KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, G9P
货号 TMAT-0282 一键复制产品信息
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Anti-CD158D Monoclonal Antibody (6W258) 是一种 Mouse 抗体，靶向 CD158D。Anti-CD158D Monoclonal Antibody (6W258) 可用于 FCM。

Anti-CD158D Monoclonal Antibody (6W258)

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Rating icon 还可以
货号 TMAT-0282

别名 KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, G9P

Anti-CD158D Monoclonal Antibody (6W258) 是一种 Mouse 抗体，靶向 CD158D。Anti-CD158D Monoclonal Antibody (6W258) 可用于 FCM。

Anti-CD158D Monoclonal Antibody (6W258)
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产品介绍

生物活性
产品描述
Anti-CD158D Monoclonal Antibody (6W258) is a Mouse antibody targeting CD158D. Anti-CD158D Monoclonal Antibody (6W258) can be used in FCM.
别名
KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, G9P
Ig Type
IgG1
克隆号
6W258
反应种属
Human
应用FCM
推荐剂量
FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternate alleles of this gene are represented on multiple alternate reference loci (ALT_REF_LOCs). Alternative splicing results in multiple transcript variants, some of which may not be annotated on the primary reference assembly.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD158D (AA: extra 22-120) expressed in E. Coli.
抗原种属
Human
基因名称
KIR2DL4
基因ID
3805
蛋白名称
Killer cell immunoglobulin-like receptor 2DL4
Uniprot ID
Q99706
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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