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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CCNE1 Monoclonal Antibody (1J384)

Synonyms: CCNE
货号 TMAT-0231 一键复制产品信息
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Anti-CCNE1 Monoclonal Antibody (1J384) 是一种 Mouse 抗体，靶向 CCNE1。Anti-CCNE1 Monoclonal Antibody (1J384) 可用于 IHC,FCM。

Anti-CCNE1 Monoclonal Antibody (1J384)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0231

别名 CCNE

Anti-CCNE1 Monoclonal Antibody (1J384) 是一种 Mouse 抗体，靶向 CCNE1。Anti-CCNE1 Monoclonal Antibody (1J384) 可用于 IHC,FCM。

Anti-CCNE1 Monoclonal Antibody (1J384)
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产品介绍

生物活性
产品描述
Anti-CCNE1 Monoclonal Antibody (1J384) is a Mouse antibody targeting CCNE1. Anti-CCNE1 Monoclonal Antibody (1J384) can be used in IHC,FCM.
别名
CCNE
Ig Type
IgG1
克隆号
1J384
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CCNE1 (AA: 307-410) expressed in E. Coli.
抗原种属
Human
基因名称
CCNE1
基因ID
898
蛋白名称
G1/S-specific cyclin-E1
Uniprot ID
P24864
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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  • 配液 计算器
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