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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CCDC39 Polyclonal Antibody

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货号 TMAB-03745

Anti-CCDC39 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CCDC39。Anti-CCDC39 Polyclonal Antibody 可用于 WB。

Anti-CCDC39 Polyclonal Antibody

Anti-CCDC39 Polyclonal Antibody

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货号 TMAB-03745

Anti-CCDC39 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CCDC39。Anti-CCDC39 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CCDC39 Polyclonal Antibody is a Rabbit antibody targeting CCDC39. Anti-CCDC39 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton, cilium axoneme. Note=CCDC40 is required for localization to axonemes.
组织特异性Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Tissue specificity:Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis. Involvement in disease:Defects in CCDC39 are the cause of primary ciliary dyskinesia type 14 (CILD14) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CCDC39
抗原种属
Human
基因名称
CCDC39
基因ID
339829
蛋白名称
Coiled-coil domain-containing protein 39
Uniprot ID
Q9UFE4
功能
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly.
化学信息
分子量Theoretical: 110 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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