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Anti-Caveolin-2 Polyclonal Antibody

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货号 TMAB-03704

Anti-Caveolin-2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Caveolin-2。Anti-Caveolin-2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Caveolin-2 Polyclonal Antibody

Anti-Caveolin-2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03704

Anti-Caveolin-2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Caveolin-2。Anti-Caveolin-2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Caveolin-2 Polyclonal Antibody is a Rabbit antibody targeting Caveolin-2. Anti-Caveolin-2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse)
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Golgi apparatusmembrane; Peripheral membrane protein. Cell membrane; Peripheralmembrane protein. Membrane, caveola; Peripheral membrane protein.Note=Potential hairpin-like structure in the membrane. Membraneprotein of caveolae. Tyr-19-phosphorylated form is enriched atsites of cell-cell contact and is translocated to the nucleus incomplex with MAPK1 in response to insulin (By similarity).Tyr-27-phosphorylated form is located both in the cytoplasm andplasma membrane. CAV1-mediated Ser-23-phosphorylated form locatesto the plasma membrane. Ser-36-phosphorylated form resides inintracellular compartments.
组织特异性Expressed in endothelial cells, smooth musclecells, skeletal myoblasts and fibroblasts.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cellular localization: Nucleus. Cytoplasm. Golgi apparatus membrane. Cell membrane. Membrane > caveola. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Caveolin-2
抗原种属
Human
基因名称
CAV2
基因ID
858
蛋白名称
Caveolin-2
Uniprot ID
P51636
功能
May act as a scaffolding protein within caveolarmembranes. Interacts directly with G-protein alpha subunits and canfunctionally regulate their activity. Acts as an accessory proteinin conjunction with CAV1 in targeting to lipid rafts and drivingcaveolae formation. The Ser-36 phosphorylated form has a role inmodulating mitosis in endothelial cells. Positive regulator ofcellular mitogenesis of the MAPK signaling pathway. Required forthe insulin-stimulated nuclear translocation and activation ofMAPK1 and STAT3, and the subsequent regulation of cell cycleprogression (By similarity).
化学信息
分子量Theoretical: 18 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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