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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CATSPERB Polyclonal Antibody

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货号 TMAB-03699

Anti-CATSPERB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CATSPERB。Anti-CATSPERB Polyclonal Antibody 可用于 WB。

Anti-CATSPERB Polyclonal Antibody

Anti-CATSPERB Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03699

Anti-CATSPERB Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CATSPERB。Anti-CATSPERB Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-CATSPERB Polyclonal Antibody is a Rabbit antibody targeting CATSPERB. Anti-CATSPERB Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CatSpers are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. CatSper∫ is a multipass membrane protein that functions as an auxiliary protein of the CatSper channel. It contains a large extracellular domain and a number of N-glycosylation sites. CatSper∫ specifically interacts with CatSper1 and through this interaction plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CATSPERB
抗原种属
Human
基因名称
CATSPERB
基因ID
79820
蛋白名称
Cation channel sperm-associated protein subunit beta
Uniprot ID
Q9H7T0
功能
RelevanceCATSPERB is a component of a complex composed at least of CATSPER1, CATSPERB, CATSPERG and HSPA1B. CATSPERB contains at least 2 transmembrane domains and 8 N-glycosylation sites. CATSPERB is required for trafficking or formation of a stable channel complex. It is involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. There are 2 isoforms produced by alternative splicing.
化学信息
分子量Theoretical: 127 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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