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Anti-Caspase-12 Polyclonal Antibody 2

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货号 TMAB-03655

Anti-Caspase-12 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Caspase-12。Anti-Caspase-12 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Caspase-12 Polyclonal Antibody 2

Anti-Caspase-12 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-03655

Anti-Caspase-12 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Caspase-12。Anti-Caspase-12 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,970
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200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Caspase-12 Polyclonal Antibody 2 is a Rabbit antibody targeting Caspase-12. Anti-Caspase-12 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Caspase-12
抗原种属
Human
基因名称
CASP12
基因ID
100506742
蛋白名称
Inactive caspase-12
Uniprot ID
Q6UXS9
功能
Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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