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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CASP4 Polyclonal Antibody 2

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货号 TMAB-03642

Anti-CASP4 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CASP4。Anti-CASP4 Polyclonal Antibody 2 可用于 FCM。

Anti-CASP4 Polyclonal Antibody 2

Anti-CASP4 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-03642

Anti-CASP4 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CASP4。Anti-CASP4 Polyclonal Antibody 2 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CASP4 Polyclonal Antibody 2 is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody 2 can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Rabbit,Zebrafish)
应用FCM
推荐剂量
FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Caspase 4 is a 377 amino acid protein (43 kDa) that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Caspase-4 subunit p20
抗原种属
Mouse
基因名称
CASP4
基因ID
12363
蛋白名称
Caspase-4
Uniprot ID
P70343
功能
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.
化学信息
分子量Theoretical: 20/43 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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