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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-BTK Monoclonal Antibody (2A335)

Synonyms: BTK
货号 TMAT-0183 一键复制产品信息
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Anti-BTK Monoclonal Antibody (2A335) 是一种 Mouse 抗体，靶向 BTK。Anti-BTK Monoclonal Antibody (2A335) 可用于 WB,IHC,IF。

Anti-BTK Monoclonal Antibody (2A335)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0183

别名 BTK

Anti-BTK Monoclonal Antibody (2A335) 是一种 Mouse 抗体，靶向 BTK。Anti-BTK Monoclonal Antibody (2A335) 可用于 WB,IHC,IF。

Anti-BTK Monoclonal Antibody (2A335)
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产品介绍

生物活性
产品描述
Anti-BTK Monoclonal Antibody (2A335) is a Mouse antibody targeting BTK. Anti-BTK Monoclonal Antibody (2A335) can be used in WB,IHC,IF.
别名
BTK
Ig Type
IgG1
克隆号
2A335
反应种属
Human,Monkey
应用WBIHCIF
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases.All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini.BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of BTK expressed in E. Coli.
抗原种属
Human
基因名称
BTK
基因ID
695
蛋白名称
Tyrosine-protein kinase BTK
Uniprot ID
Q06187
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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