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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ATG5 Monoclonal Antibody (8Y511)

Synonyms: hAPG5, ASP, APG5-LIKE, APG5L, APG5
货号 TMAT-0119 一键复制产品信息
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Anti-ATG5 Monoclonal Antibody (8Y511) 是一种 Mouse 抗体，靶向 ATG5。Anti-ATG5 Monoclonal Antibody (8Y511) 可用于 WB,IF,FCM。

Anti-ATG5 Monoclonal Antibody (8Y511)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0119

别名 hAPG5, ASP, APG5-LIKE, APG5L, APG5

Anti-ATG5 Monoclonal Antibody (8Y511) 是一种 Mouse 抗体，靶向 ATG5。Anti-ATG5 Monoclonal Antibody (8Y511) 可用于 WB,IF,FCM。

Anti-ATG5 Monoclonal Antibody (8Y511)
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产品介绍

生物活性
产品描述
Anti-ATG5 Monoclonal Antibody (8Y511) is a Mouse antibody targeting ATG5. Anti-ATG5 Monoclonal Antibody (8Y511) can be used in WB,IF,FCM.
别名
hAPG5, ASP, APG5-LIKE, APG5L, APG5
Ig Type
IgG2a
克隆号
8Y511
反应种属
Human,Mouse
应用WBIFFCM
推荐剂量
WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景ATG5 involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugatingsystem involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essentialfor its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control afteroxidative damage, and in subsequent cellular longevity. The ATG12-ATG5 conjugate also negatively regulates theinnate antiviral immune response by blocking the type I IFN production pathway through direct association withRARRES3 and MAVS. Also plays a role in translation or delivery of incoming viral RNA to the translationapparatus. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and Tlymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II.Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocytedifferentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradationof IFT20 via the autophagic pathway
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Synthesized peptide of human ATG5 (AA: MTDDKDVLRDVWFGRIc).
抗原种属
Human
基因名称
ATG5
基因ID
9474
蛋白名称
Autophagy protein 5
Uniprot ID
Q9H1Y0
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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