购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ARHGAP24 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02825

Anti-ARHGAP24 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ARHGAP24。Anti-ARHGAP24 Polyclonal Antibody 可用于 WB。

Anti-ARHGAP24 Polyclonal Antibody

Anti-ARHGAP24 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02825

Anti-ARHGAP24 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ARHGAP24。Anti-ARHGAP24 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-ARHGAP24 Polyclonal Antibody is a Rabbit antibody targeting ARHGAP24. Anti-ARHGAP24 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell junction, focal adhesion. Cell projection. Note=Localizes to actin stress fibers. In migrating cells, localizes to membrane lamellae and protusions.
组织特异性Isoform 1 is widely expressed with a higher level in kidney. Isoform 2 is mainly expressed in endothelial cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
抗原信息
免疫原
Recombinant Protein: human ARHGAP24 protein
抗原种属
Human
基因名称
ARHGAP24
基因ID
83478
蛋白名称
Rho GTPase-activating protein 24
Uniprot ID
Q8N264
功能
Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
化学信息
分子量Theoretical: 84 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-ARHGAP24 Polyclonal Antibody | purchase Anti-ARHGAP24 Polyclonal Antibody | Anti-ARHGAP24 Polyclonal Antibody cost | order Anti-ARHGAP24 Polyclonal Antibody | Anti-ARHGAP24 Polyclonal Antibody molecular weight