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Anti-Apolipoprotein E Polyclonal Antibody

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货号 TMAB-02777

Anti-Apolipoprotein E Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Apolipoprotein E。Anti-Apolipoprotein E Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Apolipoprotein E Polyclonal Antibody

Anti-Apolipoprotein E Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02777

Anti-Apolipoprotein E Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Apolipoprotein E。Anti-Apolipoprotein E Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Apolipoprotein E Polyclonal Antibody is a Rabbit antibody targeting Apolipoprotein E. Anti-Apolipoprotein E Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants.
抗原信息
免疫原
KLH conjugated synthetic peptide: human APOE/Apo E2
抗原种属
Human
基因名称
APOE
基因ID
348
蛋白名称
Apolipoprotein E
Uniprot ID
P02649
功能
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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