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Anti-AP2 alpha Polyclonal Antibody

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货号 TMAB-02720

Anti-AP2 alpha Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AP2 alpha。Anti-AP2 alpha Polyclonal Antibody 可用于 WB。

Anti-AP2 alpha Polyclonal Antibody

Anti-AP2 alpha Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02720

Anti-AP2 alpha Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AP2 alpha。Anti-AP2 alpha Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-AP2 alpha Polyclonal Antibody is a Rabbit antibody targeting AP2 alpha. Anti-AP2 alpha Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AP2 alpha
抗原种属
Human
基因名称
TFAP2A
基因ID
蛋白名称
Transcription factor AP-2-alpha
Uniprot ID
功能
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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