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Anti-AMACR Monoclonal Antibody (7B854) 是一种 Mouse 抗体,靶向 AMACR。Anti-AMACR Monoclonal Antibody (7B854) 可用于 WB,IHC,IF。
别名 RACE
Anti-AMACR Monoclonal Antibody (7B854) 是一种 Mouse 抗体,靶向 AMACR。Anti-AMACR Monoclonal Antibody (7B854) 可用于 WB,IHC,IF。

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| 产品描述 | Anti-AMACR Monoclonal Antibody (7B854) is a Mouse antibody targeting AMACR. Anti-AMACR Monoclonal Antibody (7B854) can be used in WB,IHC,IF. |
| 别名 | RACE |
| Ig Type | IgG2b |
| 克隆号 | 7B854 |
| 反应种属 | Human,Mouse |
| 应用 | WBIHCIF |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4); also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human AMACR expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | AMACR |
| 基因ID | |
| 蛋白名称 | alpha-methylacyl-CoA racemase |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |