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Anti-ALK Monoclonal Antibody (5Y982)

Synonyms: NBLST3, CD246
货号 TMAT-0063 一键复制产品信息
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Anti-ALK Monoclonal Antibody (5Y982) 是一种 Mouse 抗体,靶向 ALK。Anti-ALK Monoclonal Antibody (5Y982) 可用于 IF,FCM。

Anti-ALK Monoclonal Antibody (5Y982)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0063

别名 NBLST3, CD246

Anti-ALK Monoclonal Antibody (5Y982) 是一种 Mouse 抗体,靶向 ALK。Anti-ALK Monoclonal Antibody (5Y982) 可用于 IF,FCM。

Anti-ALK Monoclonal Antibody (5Y982)
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产品介绍


生物活性
产品描述
Anti-ALK Monoclonal Antibody (5Y982) is a Mouse antibody targeting ALK. Anti-ALK Monoclonal Antibody (5Y982) can be used in IF,FCM.
别名
NBLST3, CD246
Ig Type
IgG1
克隆号
5Y982
反应种属
Human
应用IFFCM
推荐剂量
IF: 1/50-1/250; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human ALK (AA: 1366-1468) expressed in E. Coli.
抗原种属
Human
基因名称
ALK
基因ID
蛋白名称
ALK tyrosine kinase receptor
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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