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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-AKAP5 Polyclonal Antibody

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货号 TMAB-02401

Anti-AKAP5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AKAP5。Anti-AKAP5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-AKAP5 Polyclonal Antibody

Anti-AKAP5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02401

Anti-AKAP5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AKAP5。Anti-AKAP5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-AKAP5 Polyclonal Antibody is a Rabbit antibody targeting AKAP5. Anti-AKAP5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Lipid-anchor.
组织特异性Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates (1). Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP) (1-3). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization (4-6). Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses。
抗原信息
免疫原
KLH conjugated synthetic peptide: human AKAP5
抗原种属
Human
基因名称
AKAP5
基因ID
9495
蛋白名称
A-kinase anchor protein 5
Uniprot ID
P24588
功能
May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.
化学信息
分子量Theoretical: 47/79 (human/rat) kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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