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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-AFG3L2 Polyclonal Antibody

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货号 TMAB-02374

Anti-AFG3L2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AFG3L2。Anti-AFG3L2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-AFG3L2 Polyclonal Antibody

Anti-AFG3L2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02374

Anti-AFG3L2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 AFG3L2。Anti-AFG3L2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-AFG3L2 Polyclonal Antibody is a Rabbit antibody targeting AFG3L2. Anti-AFG3L2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrial membrane; multipass membrane protein
组织特异性Ubiquitous. Highly expressed in the cerebellar Purkinje cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AFG3L2 is a multi-pass membrane metalloprotease that contains one AAA (ATPase associated with diverse cellular activities) domain, a zinc-dependent binding motif, an RNA-binding region and an ATP/GTP binding site. Localizing to the mitochondrial membrane, AFG3L2 is ubiquitously expressed with highest expression levels in skeletal muscle and heart. AFG3L2 shares 69% similarity with the yeast Afg3 protein and 49% similarity with Paraplegin, a protein of mitochondria that is thought to be involved in signal transduction and chaperone-like activities. In mitochondria, AFG3L2 forms a complex with Paraplegin that is believed to regulate essential protein quality control. Mutations in the gene encoding either one of these proteins can result in hereditary spastic paraplegia, a degenerative spinal cord disorder that is characterized by muscle spasms, stiffness in the legs and, in some cases, incontinence.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AFG3L2
抗原种属
Human
基因名称
AFG3L2
基因ID
10939
蛋白名称
AFG3-like protein 2
Uniprot ID
Q9Y4W6
功能
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders and is a putative ATP dependent protease
化学信息
分子量Theoretical: 89 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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