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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Aconitase 1 Polyclonal Antibody

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货号 TMAB-02238

Anti-Aconitase 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Aconitase 1。Anti-Aconitase 1 Polyclonal Antibody 可用于 WB。

Anti-Aconitase 1 Polyclonal Antibody

Anti-Aconitase 1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02238

Anti-Aconitase 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Aconitase 1。Anti-Aconitase 1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Aconitase 1 Polyclonal Antibody is a Rabbit antibody targeting Aconitase 1. Anti-Aconitase 1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Aconitase 1/IRP-1
抗原种属
Human
基因名称
ACO1
基因ID
48
蛋白名称
Cytoplasmic aconitate hydratase
Uniprot ID
P21399
功能
Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
化学信息
分子量Theoretical: 98 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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