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Anti-5HT3A Receptor Polyclonal Antibody 3

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货号 TMAB-02108

Anti-5HT3A Receptor Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 5HT3A Receptor。Anti-5HT3A Receptor Polyclonal Antibody 3 可用于 WB。

Anti-5HT3A Receptor Polyclonal Antibody 3

Anti-5HT3A Receptor Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-02108

Anti-5HT3A Receptor Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 5HT3A Receptor。Anti-5HT3A Receptor Polyclonal Antibody 3 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,975
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200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-5HT3A Receptor Polyclonal Antibody 3 is a Rabbit antibody targeting 5HT3A Receptor. Anti-5HT3A Receptor Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
组织特异性Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
抗原信息
免疫原
KLH conjugated synthetic peptide: human 5HT3A Receptor
抗原种属
Human
基因名称
HTR3A
基因ID
3359
蛋白名称
5-hydroxytryptamine receptor 3A
Uniprot ID
P46098
功能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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