18-Oxocortisol

Name: 18-Oxocortisol
Brand: TargetMol
SKU: T39991
Rating: 4.5 (1 reviews)

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产品编号 T39991Cas号 2410-60-8

18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.

18-Oxocortisol

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产品编号 T39991Cas号 2410-60-8

18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.

规格	价格	库存	数量
2 mg	¥ 8,990	待询

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产品描述	18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling.
体内活性	Administration of 18-oxocortisol to rats induces a mineralocorticoid-type hypertension with hypokalemia, cardiac and renal enlargement and cardiovascular lesions. Administration of 18-oxocortisol to sheep also causes a rapid increase in blood pressure. However, the doses required for increasing blood pressure are high[3].