(S)-N3-HABA (DCHA) is a reagent used in click chemistry, notable for its application in bonding nucleic acids, lipids, proteins, and other molecules due to its high yield, specificity, and simplicity. This compound contains an Azide group, enabling a copper-catalyzed Azide-Alkyne Cycloaddition (CuAAC) with molecules that have an Alkyne group, as well as a Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.