精选先导化合物类似物库

A new approach to the design of our largest screening library aims to deliver the most reliable source of initial hits. Each compound in the library passed stringent MedChem filters, QC control, and visual inspection of a substance. The sophisticated construction of this HTS Library allows you to get initial SAR data immediately after a first screen and will help you to determine safe hits, which you can follow more securely than any other from commercial diversity libraries. The main focus at medicinal chemistry hand was fixed on the lead-like molecules to give more space for the evolution of identified hits. These compounds in Elite Library have been screened against a panel of early ADMET tests (including DMSO and water solubility, PAMPA, PGP, and CYP inhibition) to make sure screening hits are devoid of potential ADMET problems and are amenable for rapid hit-to-lead optimization.

• 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
• 干粉蓝冰运输，DMSO溶液干冰运输；
• 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。