Name: 细胞重编程化合物库
Brand: TargetMol
SKU: L8110

细胞重编程化合物库

Reprogramming Compound Library

很棒

产品编号 L8110

细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。

TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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Apoptosis

Autophagy

PI3K

VEGFR

EGFR

HDAC

mTOR

p38 MAPK

JAK

ERK

Akt

Wnt/beta-catenin

STAT

Histone Methyltransferase

Epigenetic Reader Domain

PDGFR

AMPK

GSK-3

Raf

FGFR

Src

CDK

NF-κB

TGF-beta/Smad

Endogenous Metabolite

MAPK

FLT

c-Met/HGFR

c-Kit

JNK

Ras

MEK

ROCK

PKC

Reactive Oxygen Species

Antibacterial

HIF/HIF Prolyl-Hydroxylase

DNA-PK

DNA/RNA Synthesis

Tyrosine Kinases

Nucleoside Antimetabolite/Analog

Hedgehog/Smoothened

S6 Kinase

Parasite

ALK

Monoamine Oxidase

Bcr-Abl

Mitochondrial Metabolism

ATM/ATR

PKA

c-RET

HIF

PDK

TNF

MAO

COX

Calcium Channel

Aurora Kinase

Antibiotic

HIV Protease

Influenza Virus

Dehydrogenase

c-Myc

Caspase

TLR

Potassium Channel

HER

Mitophagy

Sirtuin

Casein Kinase

Pim

Rho

Histone Acetyltransferase

Kras

Virus Protease

PARP

Gamma-secretase

IGF-1R

Retinoid Receptor

PPAR

Smo

Cytochromes P450

PI4K

PERK

HSV

IL Receptor

MMP

c-Fms

TAM Receptor

Ferroptosis

Antifungal

Phosphatase

Bcl-2 Family

PDE

MNK

Beta Amyloid

FAK

IκB/IKK

Syk

DNA Methyltransferase

Sodium Channel

MLK

NO Synthase

HCV Protease

Antioxidant

ROS

Chk

Trk receptor

Nrf2

AChR

Microtubule Associated

Adrenergic Receptor

SIK

PTEN

p53

Histone Demethylase

Serine/threonin kinase

CSF-1R

Drug Metabolite

Interleukin

MELK

PROTACs

DYRK

Histamine Receptor

Tie-2

TOPK

HBV

Topoisomerase

LDL

Antifection

CaMK

Antiviral

Ephrin Receptor

ASK

5-HT Receptor

PLK

Tyrosinase

Carbonic Anhydrase

Transferase

Estrogen/progestogen Receptor

Adenosine Receptor

IFNAR

Serine Protease

TRP/TRPV Channel

Glucosidase

Lipoxygenase

Prostaglandin Receptor

Porcupine

SARS-CoV

Reverse Transcriptase

SGK

ATPase

Proton pump

NOS

Dopamine Receptor

Integrin

NADPH

GTPase

Estrogen Receptor/ERR

PYK2

Aryl Hydrocarbon Receptor

RIP kinase

Cholinesterase (ChE)

P-gp

transporter

KLF

GABA Receptor

Cannabinoid Receptor

Discoidin Domain Receptor (DDR)

ROS Kinase

BTK

GPCR

Chloride channel

Adenylyl Cyclase

RAR/RXR

ROR

MyD88

BACE

RAAS

Cholecystokinin Receptor

Hck

FXR

IRE1

Myosin

GRK

Guanylate cyclase

DNA Alkylation

CCR

ACK1

cAMP

GluR

DNA

DUB

ATP Citrate Lyase

Lipid

Beta-Secretase

HSP

PAI-1

Hippo pathway

Phospholipase

NADPH-oxidase

NOD

IRAK

PD-1/PD-L1

Apelin receptor

Mdm2

NPC1L1

DHFR

Dynamin

Ligands for Target Protein for PROTAC

YAP

Arginase

Na+/Ca2+ Exchanger

Lipase

gp120/CD4

Glutathione Peroxidase

OCT

MRP

AAK1

Antifolate

Glucocorticoid Receptor

Immunology/Inflammation related

iGluR

E1/E2/E3 Enzyme

UGT

NMDAR

ABC Transporter

Hexokinase

Opioid Receptor

MAGL

Fatty Acid Synthase

FAAH

CXCR

Thrombopoietin Receptor

Androgen Receptor

SGLT

BCRP

PGE Synthase

Acyltransferase

STING

LRRK2

Decarboxylase

hCE

Methionine Adenosyltransferase (MAT)

Carboxypeptidase

GPX

Aromatase

CRISPR/Cas9

Hydroxylase

RXFP receptor

Gap Junction Protein

DAPK

Anti-infection

BMI-1

Protease-activated Receptor

p97

AhR

NOD-like Receptor (NLR)

CFTR

Imidazoline Receptor

Kinesin

S1P Receptor

ADC Cytotoxin

细胞重编程化合物库

产品编号 L8110

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