细胞重编程化合物库

细胞重编程化合物库

Reprogramming Compound Library

很棒

产品编号 L8110

细胞重编程指的是已分化的体细胞在一定条件下被逆转恢复到多能或全能性状态的过程。传统的重编程技术存在整合外源基因等问题在临床应用中存在局限性，而小分子化合物诱导多能干细胞的研究开辟了一条全新的体细胞重编程方法。小分子化合物诱导重编程的优点包括：不整合到基因组，无免疫原性；可以透过细胞膜直接作用于靶点，操作方便；效应可逆，可同时调控多个靶点，精确调控细胞命运。小分子化合物诱导的多能干细胞在药物发现、细胞治疗、疾病建模中具有很大的潜力，为治疗重大疾病开辟了新的途径。

TargetMol 细胞重编程化合物库是2240 种细胞重编程相关信号通路的生物活性小分子化合物的特有集合，为细胞重编程研究提供有效工具

TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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Apoptosis

Autophagy

PI3K

VEGFR

Ras

EGFR

HDAC

p38 MAPK

mTOR

ERK

JAK

Akt

Wnt/beta-catenin

PDGFR

Epigenetic Reader Domain

STAT

Histone Methyltransferase

AMPK

GSK-3

Endogenous Metabolite

Raf

NF-κB

FGFR

CDK

Src

TGF-beta/Smad

c-Met/HGFR

FLT

c-Kit

Antibacterial

MAPK

JNK

PKC

ROCK

MEK

Reactive Oxygen Species

HIF/HIF Prolyl-Hydroxylase

Kras

DNA/RNA Synthesis

Parasite

Nucleoside Antimetabolite/Analog

DNA-PK

Tyrosine Kinases

S6 Kinase

Hedgehog/Smoothened

Monoamine Oxidase

Bcr-Abl

Mitochondrial Metabolism

ALK

ATM/ATR

TNF

PKA

Virus Protease

COX

c-RET

Caspase

HIF

HIV Protease

PDK

Antibiotic

Calcium Channel

Dehydrogenase

MAO

Influenza Virus

c-Myc

Aurora Kinase

Mitophagy

TLR

Bcl-2 Family

Casein Kinase

Histone Acetyltransferase

Potassium Channel

HER

PERK

PARP

Sirtuin

PPAR

Gamma-secretase

Smo

Cytochromes P450

IGF-1R

c-Fms

PI4K

Phosphatase

Pim

Rho

Retinoid Receptor

Ferroptosis

Antifungal

HSV

MMP

TAM Receptor

IL Receptor

Interleukin

Beta Amyloid

DNA Methyltransferase

FAK

NO Synthase

PDE

MNK

IκB/IKK

Microtubule Associated

HCV Protease

PTEN

AChR

Syk

Sodium Channel

MLK

Antioxidant

Tie-2

Adrenergic Receptor

Drug Metabolite

ROS

Chk

Trk receptor

Nrf2

MDM-2/p53

Histone Demethylase

Serine/threonin kinase

SIK

SARS-CoV

p53

ATPase

PROTACs

IFNAR

DYRK

CSF-1R

Topoisomerase

Antifection

HSP

MELK

Tyrosinase

Transferase

Histamine Receptor

TOPK

HBV

Serine Protease

TRP/TRPV Channel

LDL

Glucosidase

CaMK

OXPHOS

Antiviral

Ephrin Receptor

ASK

Reverse Transcriptase

5-HT Receptor

GABA Receptor

PLK

Cannabinoid Receptor

Proton pump

Carbonic Anhydrase

Estrogen/progestogen Receptor

Adenosine Receptor

PYK2

Lipoxygenase

Prostaglandin Receptor

Porcupine

transporter

SGK

Anti-infection

ROS Kinase

BTK

Dopamine Receptor

Integrin

MyD88

NADPH

GTPase

Estrogen Receptor/ERR

FXR

Aryl Hydrocarbon Receptor

Myosin

RIP kinase

Cholinesterase (ChE)

ATP Citrate Lyase

Lipid

P-gp

Hippo pathway

FKBP

KLF

Discoidin Domain Receptor (DDR)

IRAK

PD-1/PD-L1

GPCR

Chloride channel

Adenylyl Cyclase

NOS

RAR/RXR

ROR

BACE

RAAS

Glutathione Peroxidase

Cholecystokinin Receptor

Hck

IRE1

UGT

GRK

Guanylate cyclase

Opioid Receptor

DNA Alkylation

PAK

FAAH

CCR

Angiotensin-converting Enzyme (ACE)

cAMP

GluR

DNA

DUB

Beta-Secretase

PAI-1

Methionine Adenosyltransferase (MAT)

Phospholipase

NADPH-oxidase

NOD

NOD-like Receptor (NLR)

PGK1

Apelin receptor

Mdm2

NPC1L1

DHFR

Dynamin

Amino Acids and Derivatives

Y Box Binding Protein 1

Ligands for Target Protein for PROTAC

YAP

Arginase

Na+/Ca2+ Exchanger

Lipase

Necroptosis

gp120/CD4

OCT

MRP

AAK1

Antifolate

NR4A

IDO

Glucocorticoid Receptor

Immunology/Inflammation related

iGluR

Prolyl Endopeptidase (PREP)

E1/E2/E3 Enzyme

NMDAR

ABC Transporter

Na-K-Cl cotransporter

Hexokinase

Molecular Glues

MAGL

Fatty Acid Synthase

ACK1

CXCR

Cadherin

Thrombopoietin Receptor

Indoleamine 2,3-Dioxygenase (IDO)

Androgen Receptor

SGLT

BCRP

PGE Synthase

Survivin

Acyltransferase

STING

LRRK2

Aminopeptidase

Decarboxylase

hCE

Pyroptosis

Carboxypeptidase

GPX

Aromatase

CRISPR/Cas9

Hydroxylase

RXFP receptor

Gap Junction Protein

DAPK

BMI-1

Protease-activated Receptor

p97

AhR

CFTR

Imidazoline Receptor

Kinesin

S1P Receptor

ADC Cytotoxin

产品编号 L8110

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