Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sodium 2-oxopropanoate (Sodium pyruvate) 是 pyruvate 的钠盐形式。pyruvate 是葡萄糖的三碳代谢物,是一种在糖酵解途径中产生的化合物,它是一种能够清除 ROS 的自由基清除剂。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 g | ¥ 163 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 195 | 现货 |
产品描述 | Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease. |
体内活性 | Sodium pyruvate nasal spray was effective in attenuating the rhinoconjunctivitis symptoms and reducing the rescue medication use of allergic rhinitis patients[1]. |
动物实验 | In the pollen season, all the participants were given corticosteroid nasal spray of standard dose for two weeks, and during the next two weeks they were randomized to treatment group (n = 23) taking nasal sodium pyruvate, and control group (n = 30) without sodium pyruvate.?Daily rhinoconjunctivitis symptom score and daily rescue medication score were analyzed.?Also the fraction of exhaled nitric oxide of the upper airway was measured before and after the treatment of sodium pyruvate[1]. |
别名 | Sodium pyruvate, 丙酮酸钠 |
分子量 | 110.04 |
分子式 | C3H3NaO3 |
CAS No. | 113-24-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.1 mg/mL (10 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 9.0876 mL | 45.438 mL | 90.876 mL | 227.1901 mL |
5 mM | 1.8175 mL | 9.0876 mL | 18.1752 mL | 45.438 mL | |
10 mM | 0.9088 mL | 4.5438 mL | 9.0876 mL | 22.719 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Sodium 2-oxopropanoate 113-24-6 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species Endogenous Metabolite Sodium pyruvate 丙酮酸钠 Inhibitor Sodium Pyruvate radical free Sodium 2oxopropanoate inhibit ROS scavenger Sodium 2 oxopropanoate Glycolysis Glucose inhibitor