cvid-4

BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI TNFRSF13B) and BAFF receptor (BAFF R BR3 TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.

Expression system: HEK293 Cells
Length: 7-71, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 2-71, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 2-71, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 6-71, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: ELISA

CD20 Protein, Human, Recombinant (TrxA), Biotinylated is expressed in E. coli expression system with TrxA tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A024R507.

CD19 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 58.65 kDa and the accession number is NP_001171569.1.

Expression system: HEK293 Cells
Length: 213-297, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-291, Extracellular Domain
Activity: Not Tested

CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses.Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.

CD20 Protein, Human, Recombinant (TrxA) is expressed in E. coli expression system with TrxA tag. The predicted molecular weight is 23.9 kDa and the accession number is A0A024R507.

CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.