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Search Results for " chymotrypsin-like "

Targets Recommended: Proteasome

27

抑制剂 & 化合物

3

天然产物

1

化合物库

23

重组蛋白

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Cat. No.	Product Name
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

化合物库

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

Cat. No.	Product Name	Target	Signaling Pathways
T17011	TCH-165	Proteasome	Proteases/Proteasome; Ubiquitination
	TCH-165 是一种蛋白酶体组装的小分子调节剂，可增加游离 20S 水平，进而增强 IDP 蛋白水解。
T21854	Proteasome inhibitor IX PS-IX,AM114	Proteasome	Proteases/Proteasome; Ubiquitination
	Proteasome inhibitor IX (PS-IX) 是 Chalcone 的一种衍生物，对20S 蛋白酶体的胰凝乳蛋白酶样活性有抑制作用，IC50约为 1 μM。它抑制 HCT116 p53+/+细胞生长，IC50为 1.49 μM，显示出有效的抗癌活性。
T6027	Delanzomib 德兰佐米,CEP-18770	Apoptosis; NF-κB; Proteasome	Apoptosis; NF-κB; Proteases/Proteasome; Ubiquitination
	Delanzomib (CEP-18770) 是一种强效的具有口服活性的蛋白酶体的胰凝乳蛋白酶样活性抑制剂，IC50为 3.8 nM。它抑制NF-κB 活性，诱导癌细胞凋亡，具有很强的抗血管生成和抗癌活性。
T6941	PI-1840 PI 1840	PARP; Proteasome	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination
	PI-1840 是一种高效的、选择性的蛋白酶体chymotrypsin-like (CT-L)抑制剂，IC50=27nM。
T7016	VR23	Apoptosis; Proteasome; Caspase	Apoptosis; Proteases/Proteasome; Ubiquitination
	VR23 是一种蛋白酶体抑制剂，对胰蛋白酶样蛋白酶体、糜蛋白酶样蛋白酶体和半胱天冬酶样蛋白酶体的 IC50 分别是1 nM、50-100 nM 和3 μM。
T63321	20S Proteasome activator 1	Proteasome	Proteases/Proteasome; Ubiquitination
	20S Proteasome activator 1 是一种 20S 蛋白酶激活剂，对胰蛋白酶样位点、胰凝乳蛋白酶样位点和半胱天冬酶位点的 IC50 分别为 0.3 μM、0.7 μM 和 1.8 μM。20S Proteasome activator 1 通过在细胞系统中翻译来防止致病性 α-synuclein A53T 突变体积累从而减少疾病发生的概率。20S Proteasome activator 1 可用于研究神经退行性疾病。
T2016	MLN9708 Ixazomib Citrate	Proteasome	Proteases/Proteasome; Ubiquitination
	MLN9708 (Ixazomib Citrate) 抑制 20S 蛋白酶体的糜蛋白酶样蛋白水解 (β5) 位点 (Ki50=0.93 nM, IC50=3.4 nM/)。 MLN9708 的生物活性形式是水溶液或血浆中的 MLN2238。
T8350	TPCK	Proteasome	Proteases/Proteasome; Ubiquitination
	TPCK 是丝氨酸蛋白酶抑制剂，通过与 HPV-18 E7 蛋白的视网膜母细胞瘤蛋白 (RB) 结合核心发生反应，并能够消除其 RB 结合能力。将它添加到培养基内，可修饰活角质形成细胞中的 E7 蛋白。
T2122	Ixazomib 艾沙佐米,MLN2238	Proteasome; Caspase; Autophagy	Apoptosis; Autophagy; Proteases/Proteasome; Ubiquitination
	Ixazomib (MLN2238) 含硼肽蛋白酶体抑制剂(PI)，可抑制 20S 蛋白酶体的糜蛋白酶样蛋白水解 (β5) 位点，IC50为 3.4 nM，Ki 为 0.93 nM。它还抑制半胱天冬酶样 (β1) 和胰蛋白酶样 (β2) 蛋白水解位点，IC50值为 31和3500 nM。
T21617	MG-115 Z-LL-Nva-CHO	Proteasome	Proteases/Proteasome; Ubiquitination
	MG-115 (Z-LL-Nva-CHO) 是一种有效且可逆的蛋白酶体抑制剂，对20S 和26S 蛋白酶体的 Ki 值分别为 21 nM 和 35 nM。MG-115 特异性抑制蛋白酶体的胰凝乳蛋白酶样活性，诱导 p53 依赖性细胞凋亡。
T36352	Suc-Leu-Tyr-AMC
	Suc-Leu-Tyr-AMC 是钙蛋白酶 I 和 II 以及木瓜蛋白酶（另一种半胱氨酸蛋白酶）的荧光底物，用于测量 20S 蛋白酶体的糜蛋白酶样肽酶活性（Ex-max：360 nm；Em-max：460 nm）。Suc-Leu-Tyr-AMC 也能被大肠杆菌的 Ti 蛋白酶裂解。
T26202	SP-Chymostatin B alpha-Mapi
	SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. It is effective at a final concentra
T37418	Z-LLL-AMC
	Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core. Chymotrypsin-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLL-AMC is typically used in cell lysates after experimental treatment.
TP1308	Suc-Leu-Leu-Val-Tyr-AMC
	Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases.
T80102	Z-Leu-Leu-Tyr-COCHO	Proteasome	Proteases/Proteasome; Ubiquitination
	Z-Leu-Leu-Tyr-COCHO为胰凝乳蛋白酶样活性抑制剂，具有Ki值为3.0 nM的高效性。
T36338	AAF-CMK (trifluoroacetate salt)
	Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at 50 μM.
T62080	GSK3494245
	GSK3494245 (DDD01305143) 是一种有效的、选择性的、口服具有活力的、可在夹在 β4 和 β5 亚基之间的位点结合寄生虫蛋白酶体 (proteasome) 的糜蛋白酶样活性抑制剂，能够作用于 WTL.donovani 蛋白酶体，其 IC50 值为 0.16μM。GSK3494245 表现出良好的生物安全特性。GSK3494245 对人蛋白酶体的糜蛋白酶样活性具有适当的抑制作用 (IC50: 26S=13 μM；富集的 THP-1 提取物 IC50=40 μM)。
T62479	3CPLro-IN-1
	3CPLro-IN-1 (compound A17) 是一种有效的、口服具有活力的 SARS-CoV-2 3CLpro 抑制剂 (IC50: 5.65 μM)。3-糜蛋白酶样半胱氨酸蛋白酶 (3CLpro) 是一种病毒复制中不可或缺的蛋白质，是一种有吸引力的、对抗 COVID-19 的药物靶点。
T74878	Enzyme-IN-1
	Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。
T63760	3CPLro-IN-2
	3CPLro-IN-2 是有效的、口服具有活力的 SARS-CoV-2 3CLpro 抑制剂 (IC50: 1.55 μM, Ki: 6.09 μM)。3-糜蛋白酶样半胱氨酸蛋白酶 (3CLpro) 是病毒复制中不可或缺的蛋白质，是有潜力的对抗 COVID-19 的药物靶点。
T81372	Proteasome-activating peptide 1
	Proteasome-activating peptide 1 是一种肽，其作用是提升胰凝乳蛋白酶样蛋白酶体（proteasome）的催化活性，有效增强体外及细胞培养环境下的蛋白质降解效率。此外，该肽能阻止肌萎缩侧索硬化症（Amyotrophic Lateral Sclerosis, ALS）细胞模型中蛋白质的过度聚集。
T81711	N-Acetyl-DL-phenylalanine β-naphthyl ester
	N-Acetyl-DL-phenylalanine β-naphthyl ester 为一芳香族氨基酸酯，用作糜蛋白酶及微生物丝氨酸蛋白酶（例如枯草杆菌蛋白酶）的显色底物。
T78640	Z-LLF-CHO Z-Leu-Leu-Phe-CHO	Proteasome	Proteases/Proteasome; Ubiquitination
	Z-LLF-CHO（Z-Leu-Leu-Phe-CHO）为垂体多催化蛋白酶复合物所具有的胰凝乳蛋白酶样活性提供有效抑制，具有Ki值为460 nM。此外，Z-LLF-CHO同样作为NF-κB核转位的抑制剂。
T76243	Proteasome-activating peptide 1 TFA
	Proteasome-activating peptide 1 TFA 是一种肽类蛋白酶体激活剂，能显著增强胰凝乳蛋白酶样蛋白酶体的催化活性，进而提升体外及培养环境中的蛋白质水解效率。此外，Proteasome-activating peptide 1 TFA 还能有效阻止肌萎缩侧索硬化症细胞模型内的蛋白质聚集现象。
T80735	Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Proteases/Proteasome; Ubiquitination
	Z-Gly-Pro-Phe-Leu-CHO（Z-GPFL-CHO）是一种具有高选择性和高效率的四肽醛类蛋白酶体抑制剂，优先抑制支链氨基酸（Ki为1.5 µM），对小中性氨基酸的Ki值为2.3 µM，胰凝乳蛋白酶样活性的Ki值为40.5 µM，对肽基-谷氨酰肽水解活性的IC50为3.1 µM。
T69288	CEP-7055
	CEP-18770 is an orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome, with potential antineoplastic activity. Proteasome inhibitor CEP 18770 represses the proteasomal degradation of a variety of proteins, including inhibitory kappaBalpha (IkappaBalpha), resulting in the cytoplasmic sequestration of the transcription factor NF-kappaB; inhibition of NF-kappaB nuclear translocation and transcriptional up-regulation of a variety of cel...
T73986	ONX-0914 TFA
	ONX-0914 (PR-957) TFA 为针对免疫蛋白酶体中的LMP7（低分子量多肽-7）的选择性抑制剂，LMP7为类糜蛋白酶亚单位。该化合物通过抑制细胞因子产生，减缓实验性关节炎进展，并已证实为分枝杆菌蛋白酶体的非竞争性不可逆抑制剂（Ki=5.2 μM）。此外，ONX-0914 TFA 能通过HSF-1介导的p-TEFb活化，激活潜伏的HIV-1。

化合物

Cat.No: T17011

Target: Proteasome

Proteasome inhibitor IX

Cat.No: T21854

Synonym: PS-IX,AM114

Target: Proteasome

Cat.No: T6027

Synonym: 德兰佐米,CEP-18770

Target: Apoptosis, NF-κB, Proteasome

Cat.No: T6941

Synonym: PI 1840

Target: PARP, Proteasome

Cat.No: T7016

Target: Apoptosis, Proteasome, Caspase

20S Proteasome activator 1

Cat.No: T63321

Target: Proteasome

Cat.No: T2016

Synonym: Ixazomib Citrate

Target: Proteasome

Cat.No: T8350

Target: Proteasome

Cat.No: T2122

Synonym: 艾沙佐米,MLN2238

Target: Proteasome, Caspase, Autophagy

Cat.No: T21617

Synonym: Z-LL-Nva-CHO

Target: Proteasome

Suc-Leu-Tyr-AMC

Cat.No: T36352

SP-Chymostatin B

Cat.No: T26202

Synonym: alpha-Mapi

Cat.No: T37418

Suc-Leu-Leu-Val-Tyr-AMC

Cat.No: TP1308

Z-Leu-Leu-Tyr-COCHO

Cat.No: T80102

Target: Proteasome

AAF-CMK (trifluoroacetate salt)

Cat.No: T36338

Cat.No: T62080

Cat.No: T62479

Cat.No: T74878

Cat.No: T63760

Proteasome-activating peptide 1

Cat.No: T81372

N-Acetyl-DL-phenylalanine β-naphthyl ester

Cat.No: T81711

Cat.No: T78640

Synonym: Z-Leu-Leu-Phe-CHO

Target: Proteasome

Proteasome-activating peptide 1 TFA

Cat.No: T76243

Z-Gly-Pro-Phe-Leu-CHO

Cat.No: T80735

Synonym: Z-GPFL-CHO

Target: Proteasome

Cat.No: T69288

Cat.No: T73986

Cat. No.	Product Name	Target	Signaling Pathways
TN3228	7-Hydroxy-3-(4-hydroxybenzyl)chroman	Others	Others
	7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome.
T10238	Aclacinomycin A hydrochloride 盐酸阿柔比星,Aclarubicin hydrochloride	Proteasome	Proteases/Proteasome; Ubiquitination
	Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinomycin A hydrochloride is also a dual inhibitor of topoisomerase I and II.
TN5655	Broussonin B
	Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin B can induce neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, and show moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.B

天然产物

7-Hydroxy-3-(4-hydroxybenzyl)chroman

Cat.No: TN3228

Target: Others

Aclacinomycin A hydrochloride

Cat.No: T10238

Synonym: 盐酸阿柔比星,Aclarubicin hydrochloride

Target: Proteasome

Cat.No: TN5655

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03653	CTRL Protein, Human, Recombinant (His) CTRL1,chymotrypsin-like	Human	HEK293 Cells
	CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is responsible for inducing endothelial inflammatory phenotypic changes possibly by upregulation of cell adhesion molecule expressions, activation of cellular protease, and induction of extracellular regulated kinase phosphorylation. Activated microglia have been observed in variou...
TMPH-02582	CELA2A Protein, Mouse, Recombinant (His) Elastase-2A,ELA2A,CELA2A,Chymotrypsin-like...	Mouse	E. coli
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.7 kDa and the accession number is P05208.
TMPH-01095	CELA2B Protein, Human, Recombinant (His & SUMO) Chymotrypsin-like elastase family member 2...	Human	E. coli
	Acts upon elastin. CELA2B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.8 kDa and the accession number is P08218.
TMPH-01094	CELA2A Protein, Human, Recombinant (His) Chymotrypsin-like elastase family member 2...	Human	P. pastoris (Yeast)
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P08217.
TMPH-01093	CELA2A Protein, Human, Recombinant (E. coli, His) Elastase-2A,CELA2A,Chymotrypsin-like elast...	Human	E. coli
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P08217.
TMPJ-00481	CELA3A Protein, Human, Recombinant (His) Elastase-3A,ELA3A,Elastase IIIA,CELA3A,Chymotrypsin...	Human	HEK293 Cells
	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little e...
TMPH-01097	CELA3B Protein, Human, Recombinant (His) Elastase IIIB,ELA3B,Protease E,Elastase-3B,CELA3B,Chymot...	Human	E. coli
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.3 kDa and the accession number is P08861.
TMPH-01096	CELA3A Protein, Human, Recombinant (His & SUMO) Elastase-3A,Protease E,ELA3,Chymotrypsin-like	Human	E. coli
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.6 kDa and the accession number is P09093.
TMPH-02583	CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc) Elastase-3B,Elastase IIIB,Protease E,Chymotrypsin-<...	Mouse	E. coli
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.1 kDa and the accession number is Q9CQ52.
TMPH-02584	CELA3B Protein, Mouse, Recombinant (His & Myc) ELA3B,Chymotrypsin-like elastase family me...	Mouse	P. pastoris (Yeast)
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Mouse, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 29.6 kDa and the accession number is Q9CQ52.
TMPH-00209	CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc) clpP-2,Endopeptidase Clp 2,ATP-dependent Clp protease proteo...	Borrelia burgdorferi	E. coli
	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPH-00582	Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc) clpP,ATP-dependent Clp protease proteolytic subunit,Endopept...	E. coli	E. coli
	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
TMPH-03329	Mcpt2 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates. Mcpt2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P00770.
TMPJ-01431	SARS-CoV-2 Papain-Like Protease Protein PLpro,PL-PRO,pp1a,Replicase polyprotein 1a,Papain-like	SARS-CoV-2	E. coli
	Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NS3) sect...
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-\|-His-9' bond of angiotensin I and the 'Phe-4-\|-Ala-5' and 'Tyr-10-\|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPY-01363	Serpin A11 Protein, Mouse, Recombinant (His) serpin peptidase inhibitor, clade A (α-1 antiproteinase, ant...	Mouse	HEK293 Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi...
TMPY-01855	Serpin A10 Protein, Mouse, Recombinant (His) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,...	Mouse	HEK293 Cells
	Protein Z-dependent protease inhibitor, also known as PZ-dependent protease inhibitor, SERPINA1 and ZPI, is a secreted protein that belongs to the serpin family. It is expressed by the liver and secreted in plasma. SERPINA1 / Serpin-A1 inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because ...
TMPY-01841	Serpin I2 Protein, Human, Recombinant (His) PI14,TSA2004,PANCPIN,MEPI,Serpin I2,serpin peptidase inhibit...	Human	HEK293 Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chy...
TMPY-02712	Serpin B3 Protein, Human, Recombinant (His) T4-A,HsT1196,serpin peptidase inhibitor, clade B (ovalbumin)...	Human	Baculovirus Insect Cells
	SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be...
TMPY-01589	Serpin B10 Protein, Mouse, Recombinant (His) Serpinb10-ps,serpin peptidase inhibitor, clade B (ovalbumin)...	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi...
TMPY-01893	Serpin A12 Protein, Human, Recombinant (His) OL-64,serpin peptidase inhibitor, clade A (α-1 antiproteinas...	Human	HEK293 Cells
	Serpins are the largest and most diverse family of protease inhibitors. Most serpins control proteolytic cascades, certain serpins do not inhibit enzymes, but instead perform diverse functions such as storage (ovalbumin, in egg white), hormone carriage proteins (thyroxine-binding globulin, cortisol-binding globulin) and tumor suppressor genes (maspin). Most inhibitory serpins target chymotrypsin-like serine proteases. These enzymes are defined by the presence of a nucleophilic serine residue in ...
TMPY-01632	Serpin B4 Protein, Mouse, Recombinant (His) Serpinb4,1110001H02Rik,1110013A16Rik,Serpinb3c,Scca2,serine ...	Mouse	Baculovirus Insect Cells
	Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi...
TMPY-01027	Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) carnitine palmitoyltransferase 1B (muscle),AV080368,Mcp-1	Mouse	HEK293 Cells
	Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...

重组蛋白

CTRL Protein, Human, Recombinant (His)

Cat.No: TMPY-03653

Species: Human

Expression System: HEK293 Cells

CELA2A Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02582

Species: Mouse

Expression System: E. coli

CELA2B Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01095

Species: Human

Expression System: E. coli

CELA2A Protein, Human, Recombinant (His)

Cat.No: TMPH-01094

Species: Human

Expression System: P. pastoris (Yeast)

CELA2A Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01093

Species: Human

Expression System: E. coli

CELA3A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00481

Species: Human

Expression System: HEK293 Cells

CELA3B Protein, Human, Recombinant (His)

Cat.No: TMPH-01097

Species: Human

Expression System: E. coli

CELA3A Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01096

Species: Human

Expression System: E. coli

CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02583

Species: Mouse

Expression System: E. coli

CELA3B Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02584

Species: Mouse

Expression System: P. pastoris (Yeast)

CLPP2 Protein, Borrelia burgdorferi, Recombinant (His & Myc)

Cat.No: TMPH-00209

Species: Borrelia burgdorferi

Expression System: E. coli

Endopeptidase Clp Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00582

Species: E. coli

Expression System: E. coli

Mcpt2 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03329

Species: Rat

Expression System: E. coli

SARS-CoV-2 Papain-Like Protease Protein

Cat.No: TMPJ-01431

Species: SARS-CoV-2

Expression System: E. coli

Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02778

Species: Mouse

Expression System: E. coli

Serpin A11 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01363

Species: Mouse

Expression System: HEK293 Cells

Serpin A10 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01855

Species: Mouse

Expression System: HEK293 Cells

Serpin I2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01841

Species: Human

Expression System: HEK293 Cells

Serpin B3 Protein, Human, Recombinant (His)

Cat.No: TMPY-02712

Species: Human

Expression System: Baculovirus Insect Cells

Serpin B10 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01589

Species: Mouse

Expression System: Baculovirus Insect Cells

Serpin A12 Protein, Human, Recombinant (His)

Cat.No: TMPY-01893

Species: Human

Expression System: HEK293 Cells

Serpin B4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01632

Species: Mouse

Expression System: Baculovirus Insect Cells

Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01027

Species: Mouse

Expression System: HEK293 Cells

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