avenanthramide a

Avenanthramide A is a biochemical.

Avenanthramide D is a biochemical.

Avenanthramide E is a biochemical.

Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.

Avenanthramide C（燕麦蒽酰胺 C）是一种可口服的天然生物碱，具有抗氧化 炎症特性，可降低TNF-a、BAK、IL-1b和Bcl-2的表达；可以逆转阿尔茨海默病的记忆和行为障碍，caspase-3切割减少，pS9GSK-3β和IL-10水平上升，能够结合α1A adrenergic并刺激AMPK；能够减轻噪声和药物导致的听力损失。

Avenanthramide B 是一种天然产物，可用作天然产物对照品，用于生命科学相关领域的研究，其产品编号为 TN8487。