高通量筛选,高内涵筛选(HTS,HCS)作为目前主流的药物筛选方法,具有微量、快速、灵敏和准确等优点,可同时筛选成千上万个样品。该技术非常依赖数量庞大且结构多样性高的化合物库,同时,为了高通量筛选平台不同课题的研究方向,潜在的靶点多样性也是非常重要的一方面。
世界上商品化的化合物约有5000万个, 我们只选择质量可靠,类药性佳,多样性好的化合物为客户提供实验样本。 在化合物库的设计和筛选过程中,我们通过一系列方法,保证化合物库的多样化和高度特异性。这些库已经在我们的内部生物检测中得到了广泛的验证,并且在超过200个外部合作伙伴的实验室中得到验证,其中包括美国、欧洲和日本的制药、生物技术、学术和筛选中心。
Cat. No. | Product Name | Description | |
---|---|---|---|
LF1000 | 多样性核心预制库
Pre-plated Diversity Sets
|
For your convenience, there are Diversity Sets of 5,000, 10,000, 15,000, and 20,000 compounds with no structure overlap. | 50000 compounds |
L5610 | Golden骨架库
Golden Scaffold Library
|
多样性好,从160万个小分子中挑选而出,10000 个化合物,5000种骨架结构; | 10000 compounds |
DO1200 | 药物靶点库
SmartTM Library
|
数量多,含53200种小分子化合物,是高通量筛选的有力工具; | 53200 compounds |
DF4500 | 多样性核心库Part1
Diversity Core Library Part1
|
绝大部分分子量<500,主要集中于250-450之间,方便后续的改造优化; | 50000 compounds |
VM1400 | 多样性核心库Part2
Diversity Core Library Part2
|
分子量<500,主要集中于250-450之间,方便后续的改造优化; | 25920 compounds |
L5600 | Mini骨架库
Mini Scaffold Library
|
多样性好,从一百多万个小分子中挑选而出,5000 个化合物代表5000 种骨架结构; | 5000 compounds |
CB1100 | EXP多样性库
DIVERSet-EXP Library
|
For hit finding across different targets, against novel targets, or for the discovery of new chemical series against existing targets, ChemBridge offers up to 150,000 DIVERSet Library compounds in economical, pre-plated format. The DIVERSet Libraries are suitable for biochemical assays, phenotypic and other cell based assays, and assays using model organisms such as bacteria, yeast, c. elegans, zebrafish, or arabidopsis. DIVERSet Libraries have been used across many disease areas resulting in hundreds of citations in published research articles. | 50000 compounds |