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WEHI-3773 是一种抑制VDAC2与BAK或BAX相互作用的化合物。它通过阻断VDAC2介导的BAX向线粒体募集来抑制BAX介导的细胞凋亡 (Apoptosis),而限制VDAC2对BAK的抑制隔离则会促进BAK介导的细胞凋亡 (Apoptosis)。WEHI-3773 在抗癌研究中具有潜力。
WEHI-3773 是一种抑制VDAC2与BAK或BAX相互作用的化合物。它通过阻断VDAC2介导的BAX向线粒体募集来抑制BAX介导的细胞凋亡 (Apoptosis),而限制VDAC2对BAK的抑制隔离则会促进BAK介导的细胞凋亡 (Apoptosis)。WEHI-3773 在抗癌研究中具有潜力。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 待询 | 待询 | |
50 mg | 待询 | 待询 |
WEHI-3773 相关产品
产品描述 | WEHI-3773 is an inhibitor of the interaction between VDAC2 and either BAK or BAX. It prevents BAX-mediated apoptosis (Apoptosis) by blocking the recruitment of BAX to the mitochondria through VDAC2. Conversely, WEHI-3773 promotes BAK-mediated apoptosis (Apoptosis) by limiting VDAC2's inhibitory sequestration of BAK. This compound shows promise for research in the field of cancer therapy. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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