Name: Polymyxin B1
Brand: TargetMol
SKU: T12518
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 2,970

35日内发货

5 mg

¥ 7,670

35日内发货

10 mg

¥ 11,500

35日内发货

生物活性

产品描述	Polymyxin B1, a potent antimicrobial lipopeptide derived from Bacillus polymyxa, has potential for treating multidrug-resistant Gram-negative bacterial infections.
体外活性	Polymyxin B1 strongly inhibits protein synthesis in yeast, and in E. coli and S. aureus[4].
体内活性	The area under the concentration-time curve for Polymyxins B1 is greater than those of colistins A and B. Colistin A colistin B. The clearance value of Polymyxins B1 is 2.39 mL/min/kg, the plasma protein binding is 82.3%, the elimination half-life is 79.5 min and the AUC0-∞ is 365 mg?min/L.
别名	硫酸多粘 B1

化学信息

分子量	1203.48
分子式	C₅₆H₉₈N₁₆O₁₃
CAS No.	4135-11-9
Smiles	[H][C@@]1(CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC(=O)[C@]([H])(CCNC(=O)[C@@]([H])(NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)CCCC[C@@H](C)CC)[C@@H](C)O
密度	1.27g/cm3