gbp 1

Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secretion occurred without the presence of a leader peptide. Secretion procession is a nonclassical, likely ABC transporter-dependent, pathway and independent of GBP-1 GTPase activity and isoprenylation, and did not require additional interferon-λ-induced factors. Clinically most important was the detection of significantly increased GBP-1 concentrations in the cerebrospinal fluid of patients with bacterial meningitis as compared to control patients.

Expression system: E. coli
Length: 1-154, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-325, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 2-135, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 18-247, Full Length of Mature Protein
Activity: Not Tested

Adiponectin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.76 kDa and the accession number is A0A2K5X7X6.

Expression system: HEK293 Cells
Length: 2-135, Full Length of Mature Protein
Activity: Not Tested

Adiponectin Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is Q15848.

Adiponectin Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q60994.

Expression system: E. coli
Length: 1-135, Full Length
Activity: BLI、Hemagglutination Assay

Expression system: Baculovirus Insect Cells
Length: 1-447, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-244, Full Length
Activity: Not Tested

Adiponectin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A8K660.

Galectin-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.07 kDa and the accession number is NP_002296.1.