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5

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T82462	Enterotoxin STp (E. coli)
	Enterotoxin STp (E. coli), 热稳定肠毒素，适用于疫苗研究领域。
T72002	Carbazomycin C
	Carbazomycin C is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It is active against S. aureus, B. anthracis, B. subtilis, and M. flavus, the fungi T. asteroides and T. mentagrophytes, and P. falciparum. It is also active against a panel of five plant pathogenic fungi. Carbazomycin C is cytotoxic to MCF-7, KB, and NCI H187 cells. It also inhibits 5-lipoxygenase (5-LO) activity in RBL-1 cell extracts.
T79657	MeOIstPyrd
	MeOIstPyrd是抗皮肤癌活性分子，其作用机制包括激活线粒体内在的细胞凋亡通路，从而抑制细胞的增殖、迁移及球体形成，并能诱导DNA损伤。此外，MeOIstPyrd还能激活p53蛋白、延长其半衰期，并通过ser15位点的磷酸化增强p53的稳定性。它通过与MDM2在p53子口袋内的结合位点互作，阻断p53与MDM2的相互作用。
T4498	Stiripentol 斯利潘托,BCX2600,Diacomit	P450	Metabolism
	Stiripentol (BCX2600) 是抗惊厥剂，对 CYP3A4 (非竞争性) 及 CYP2C19 (竞争性地) 介导的 CLB 向 N-desmethylclobazam (NCLB) 的 N-去甲基化具有抑制作用。
T60526	N-Salicyloyltryptamine
	N-Salicyloyltryptamine(STP) 是一种色胺类似物，具有抗惊厥、抗炎、镇痛和血管舒张的作用。N-Salicyloyltryptamine 作为电压依赖性离子通道（包括Na+、Ca2+、K+离子通道）抑制剂，可抑制 K+电流，IC50值为 34.6 μM ( /to)。

化合物

Enterotoxin STp (E. coli)

Cat.No: T82462

Cat.No: T72002

Cat.No: T79657

Cat.No: T4498

Synonym: 斯利潘托,BCX2600,Diacomit

Target: P450

N-Salicyloyltryptamine

Cat.No: T60526

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His) HAST1/HAST2,PST,P-PST,ST1A1,STP,sulfotransferase fa...	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroids and neurotransmitters, and certain xenobiotics, including N-hydroxy-2-acetylaminoflourine and phenolic compounds, like alpha-naphthol. SULTs may be involved in the individual genetic disposition, species differences, and organotropisms for toxicological effects of chemicals. Pa...
TMPY-04127	CIp4 Protein, Human, Recombinant (His) CIP4,thyroid hormone receptor interactor 10,STOT,STP	Human	Baculovirus Insect Cells
	CIp4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 64 kDa and the accession number is Q15642-2.
TMPJ-00586	SULT1A2 Protein, Human, Recombinant (His) STP2,Aryl Sulfotransferase 2,ST1A2,Phenol Sulfotran...	Human	E. coli
	Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cytoplasmic protein and exists as a homodimer. SULT1A2 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and might thus participate as a modulating factor of cancer risk.
TMPH-01399	GSTP1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.2 kDa and...
TMPH-03306	GSTP1 Protein, Rat, Recombinant (His)	Rat	E. coli
	GSTP1 Protein, Rat, Recombinant (His) is expressed in E. coli.
TMPH-00445	GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)	Chinese hamster	P. pastoris (Yeast)
	GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His) is expressed in Yeast.
TMPH-01398	GSTP1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mo...
TMPH-00444	GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)	Chinese hamster	E. coli
	GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03022	PstP Protein, Mycobacterium tuberculosis, Recombinant	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection. PstP Protein, Mycobacterium tuberculosis, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.3 kDa and the accession number is P9WHW4.
TMPH-03021	PstP Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection.
TMPH-02683	GSTP1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
TMPJ-00499	GSTP1 Protein, Human, Recombinant GSTP1,GST3,GST class-pi,Glutathione S-transferase P...	Human	E. coli
	Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione ...

重组蛋白

SULT1A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02062

Species: Human

Expression System: E. coli

CIp4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04127

Species: Human

Expression System: Baculovirus Insect Cells

SULT1A2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00586

Species: Human

Expression System: E. coli

GSTP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01399

Species: Human

Expression System: P. pastoris (Yeast)

GSTP1 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03306

Species: Rat

Expression System: E. coli

GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)

Cat.No: TMPH-00445

Species: Chinese hamster

Expression System: P. pastoris (Yeast)

GSTP1 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01398

Species: Human

Expression System: E. coli

GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)

Cat.No: TMPH-00444

Species: Chinese hamster

Expression System: E. coli

PstP Protein, Mycobacterium tuberculosis, Recombinant

Cat.No: TMPH-03022

Species: Mycobacterium tuberculosis

Expression System: E. coli

PstP Protein, Mycobacterium tuberculosis, Recombinant (His)

Cat.No: TMPH-03021

Species: Mycobacterium tuberculosis

Expression System: E. coli

GSTP1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02683

Species: Mouse

Expression System: E. coli

GSTP1 Protein, Human, Recombinant

Cat.No: TMPJ-00499

Species: Human

Expression System: E. coli

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