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12

抑制剂 & 化合物

1

天然产物

19

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76570 PSM

PSM-β, 一种从表皮葡萄球菌中分离的活性肽,属于葡萄球菌毒素类似物,并且是酚溶性调节蛋白。该化合物展现出抑菌作用和低溶血性。
T81360 PSMα3 TFA

PSMα3 TFA 作为一种肽类化合物,主要用于诱导生成耐受性的树突细胞(DC),以应用于DC疫苗接种。该化合物能对TLR2和TLR4诱导的DC成熟过程进行调节,抑制促炎和消炎细胞因子的产生,降低抗原摄取,并影响人单核细胞来源DC的渗透和调节能力。此外,PSMα3 TFA 是耐甲氧西林金黄色葡萄球菌(MRSA)中最有毒株释放的关键毒素之一。
T38394L PSMα3 acetate(1001405-52-2 Free base)

PSMα3 acetate(1001405-52-2 Free base) 是一种肽化合物,可用于诱导树突状细胞 (DC) 对 DC 疫苗接种策略的耐受性。PSMα3 acetate 通过改变 TLR2 或 TLR4 诱导的成熟过程,有效渗透和调节人类单核细胞衍生的 DC。 此外,PSMα3 acetate 可抑制促炎细胞因子和抗炎细胞因子的产生,并减少抗原摄取。 PSMα3 acetate 是大多数致病性耐甲氧西林金黄色葡萄球菌 (MRSA) 菌株释放的重要毒力因子。
T28466 PSMA-11

HBED-CC-PSMA,Psma-hbed-CC,PSMA11

PSMA-11 (HBED-CC-PSMA)通过与前列腺特异性膜抗原(PSMA)的细胞外结构域结合来检测前列腺癌的复发和转移。PSMA-11常被用作正电子发射断层扫描(PET)中用作表达PSMA 的肿瘤的示踪剂,通过静脉注射镓Ga 68标记的PSMA-11,Glu-urea-Lys(Ahx)分子靶向并结合表达PSMA 的肿瘤细胞。内化后,PSMA 表达的肿瘤细胞可在PET 成像中被检测到。
T81361 PSMA-Val-Cit-PAB-MMAE

PSMA-Val-Cit-PAB-MMAE是一种靶向前列腺特异性膜抗原(PSMA)的小分子化合物,用MMAE作为药效基团进行前列腺癌治疗。
T78927 PSMA-IN-3

PSMA-IN-3(compound 17)是一种高亲和力的新型PSMA抑制剂,IC50为13 nM。该化合物可作为开发18F标记的放射性配体的基础,用于前列腺癌PSMA的PET成像。
T40326 PSMA–DA1

PSMA–DA1

PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.
T69924 PSMA-1007

PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.
T78412 Biotin-NH-PSMA-617

Biotin-NH-PSMA-617为标记有生物素的PSMA-617小分子,专门针对前列腺特异性膜抗原(PSMA),后者为肿瘤细胞所特有表达。
T39831 PSMA-ALB-56

PSMA-ALB-56是通过结合谷氨酸脲基 psma 结合实体、DOTA 螯合剂和基于4-(对碘苯基)-片段或 p(tolyl)-片段的白蛋白结合剂而设计的一种 PSMA-targeting 放射性配体,具有抗肿瘤活性。
T78153 PSMA I&T

Others Others
PSMAI&T为高效的前列腺特异性膜抗原(PSMA)抑制剂,适用于前列腺癌(PCa)的单光子发射计算机断层扫描(SPECT)/计算机断层扫描(CT)显像及放射性核素研究。
T28467 PSMA617-TCMC TFA

PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC

PSMA617-TCMC is a derivative of PSMA-617 with structure modification, in which the caroboxy groups in DOTA ring is replaced by TCMC macrocycle. PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.

化合物

PSM
Cat.No: T76570
Synonym:
Target:
PSMα3 TFA
Cat.No: T81360
Synonym:
Target:
PSMα3 acetate(1001405-52-2 Free base)
Cat.No: T38394L
Synonym:
Target:
PSMA-11
Cat.No: T28466
Synonym: HBED-CC-PSMA,Psma-hbed-CC,PSMA11
Target:
PSMA-Val-Cit-PAB-MMAE
Cat.No: T81361
Synonym:
Target:
PSMA-IN-3
Cat.No: T78927
Synonym:
Target:
PSMA–DA1
Cat.No: T40326
Synonym: PSMA–DA1
Target:
PSMA-1007
Cat.No: T69924
Synonym:
Target:
Biotin-NH-PSMA-617
Cat.No: T78412
Synonym:
Target:
PSMA-ALB-56
Cat.No: T39831
Synonym:
Target:
PSMA I&T
Cat.No: T78153
Synonym:
Target: Others
PSMA617-TCMC TFA
Cat.No: T28467
Synonym: PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC
Target:
Cat. No. Product Name Target Signaling Pathways
T38394 PSMα3

PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation process induced by TLR2 or TLR4. Additionally, PSMα3 inhibits the production of both pro- and anti-inflammatory cytokines and decreases antigen uptake. Notably, PSMα3 is a significant virulence factor released by the most pathogenic strains of methicillin-resistant Staphylococcus...

天然产物

PSMα3
Cat.No: T38394
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-00381 PSMA Protein, Human, Recombinant (His)

FGCP,GCP2,PSMA,GCPII,NAALAdase,folate hydrolase (pr...

Human HEK293 Cells
PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
TMPY-06960 PSMA Protein, Human, Recombinant (His & Avi), Biotinylated

GCPII,FGCP,folate hydrolase (prostate-specific membrane anti...

Human HEK293 Cells
PSMA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 82.72 kDa and the accession number is NP_004467.1.
TMPY-05269 PSMA Protein, Human, Recombinant (His), Biotinylated

PSM,GCP2,folate hydrolase (prostate-specific membra...

Human HEK293 Cells
PSMA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is Q04609-1.
TMPK-00521 PSMA Protein, Cynomolgus, Recombinant (His)

PSMA,FOLHNAALADase I,FGCP,GCPII,PSMAFGCP,N...

Cynomolgus HEK293 Cells
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 ...
TMPK-00371 PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

NAALADase I,FOLH1,GCPIImGCP,FGCP,GCP2,PSM,mGCP,NAAL...

Mouse HEK293 Cells
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Bi...
TMPK-00370 PSMA Protein, Human, Recombinant (hFc)

NAALAdase,FOLH1,FOLHNAALADase I,FGCP,mGCP,PSMAFGCP,...

Human HEK293 Cells
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Human, Recombinant (hFc) is expressed in HEK293 mamma...
TMPK-00522 PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

PSMAFGCP,PSM,NAALAdase,NAALADase I,FOLHNAA...

Cynomolgus HEK293 Cells
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His...
TMPH-00002 PSMD3 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
PSMD3 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63 kDa; 70 kDa, reducing conditions and the accession number is O43242.
TMPY-00607 PSMB6 Protein, Mouse, Recombinant (His)

proteasome (prosome, macropain) subunit, β type, 6,Mpnd,Lmp1...

Mouse E. coli
PSMB6 subunit belongs to the 20S proteasomal subunit family, which plays an importance role in the antigen presentation by MHC class I molecular. Proteasome subunit beta type 6 (PSMB6) is a member of 20S proteasomal subunit family, which forms the proteolytic core of 26S proteasome. PSMB6 knockdown decreased cellular viability under DM treatment. PSMB6 is associated with DM resistance in mosquitoes and that proteasome inhibitors such as MG-132 or bortezomib are suitable for use as a DM synergist...
TMPH-00849 PSMD14 Protein, Human, Recombinant (His & MBP)

Human Baculovirus Insect Cells
PSMD14 Protein, Human, Recombinant (His & MBP) is expressed in Baculovirus insect cells with N-MBP and C-6xHis tag. The predicted molecular weight is 79.2 kDa and the accession number is O00487.
TMPH-01928 PSMB8 Protein, Human, Recombinant (His & Myc & SUMO)

Human E. coli
PSMB8 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPY-03612 PSME1 Protein, Human, Recombinant (His)

proteasome (prosome, macropain) activator subunit 1 (PA28 al...

Human E. coli
PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunit...
TMPH-01927 PSMB2 Protein, Human, Recombinant (GST)

Human E. coli
PSMB2 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPY-03614 PSME3 Protein, Human, Recombinant (His)

PA28G,PA28-gamma,HEL-S-283,REG-GAMMA,proteasome (prosome, ma...

Human E. coli
PSME3, also known as PA28-gamma, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase su...
TMPY-04078 PSMA3 Protein, Human, Recombinant (His)

HC8,PSC3,proteasome (prosome, macropain) subunit, α type, 3,...

Human E. coli
PSMA3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.7 kDa and the accession number is AAH29402.1.
TMPY-01390 PSMA Protein, Mouse, Recombinant (His)

mopsm,folate hydrolase (prostate-specific membrane ...

Mouse HEK293 Cells
PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.
TMPK-00981 PSMP Protein, Human, Recombinant (hFc)

PC3-secreted microprotein,Msmp,Psmp

Human HEK293 Cells
PSMP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 37.9 kDa and the accession number is Q1L6U9.
TMPY-03610 PSME2 Protein, Human, Recombinant (His)

REGβ,proteasome (prosome, macropain) activator subunit 2 (PA...

Human E. coli
PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunit...
TMPK-00630 PSMP Protein, Mouse, Recombinant (hFc)

Msmp,Psmp,PC3-secreted microprotein

Mouse HEK293 Cells
PSMP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 37.9 kDa and the accession number is B1AWI6.

重组蛋白

PSMA Protein, Human, Recombinant (His)
Cat.No: TMPY-00381
Species: Human
Expression System: HEK293 Cells
PSMA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06960
Species: Human
Expression System: HEK293 Cells
PSMA Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05269
Species: Human
Expression System: HEK293 Cells
PSMA Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00521
Species: Cynomolgus
Expression System: HEK293 Cells
PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
Cat.No: TMPK-00371
Species: Mouse
Expression System: HEK293 Cells
PSMA Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00370
Species: Human
Expression System: HEK293 Cells
PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Cat.No: TMPK-00522
Species: Cynomolgus
Expression System: HEK293 Cells
PSMD3 Protein, Human, Recombinant (His)
Cat.No: TMPH-00002
Species: Human
Expression System: P. pastoris (Yeast)
PSMB6 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00607
Species: Mouse
Expression System: E. coli
PSMD14 Protein, Human, Recombinant (His & MBP)
Cat.No: TMPH-00849
Species: Human
Expression System: Baculovirus Insect Cells
PSMB8 Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01928
Species: Human
Expression System: E. coli
PSME1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03612
Species: Human
Expression System: E. coli
PSMB2 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01927
Species: Human
Expression System: E. coli
PSME3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03614
Species: Human
Expression System: E. coli
PSMA3 Protein, Human, Recombinant (His)
Cat.No: TMPY-04078
Species: Human
Expression System: E. coli
PSMA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01390
Species: Mouse
Expression System: HEK293 Cells
PSMP Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00981
Species: Human
Expression System: HEK293 Cells
PSME2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03610
Species: Human
Expression System: E. coli
PSMP Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00630
Species: Mouse
Expression System: HEK293 Cells
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