Fluopyram is an orally active succinate dehydrogenase inhibitor with antifungal and nematicidal properties. It suppresses succinate dehydrogenase activity, activates the CAR and PXR nuclear receptors, and elevates caspase-3, TNF-α, and NF-κB levels. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea, and Alternaria solani, with EC₅₀ values of 3.35, 5.389, and 0.244 µg/mL, respectively. It has been associated with liver and thyroid tumor formation and exhibits nephrotoxic and embryotoxic effects.